Thermoregulation: Fundamentals

Core knowledge on human thermoregulation, heat balance and the physiology of temperature control.

Bräuer – Anaesthesia and Thermoregulation (Springer)

Chapter from the Springer reference work "Die Anästhesiologie". Physiological thermoregulation is impaired by all anaesthetic procedures. Without preventive measures, cooling of the patient very frequently occurs in the perioperative phase. The pathophysiological consequences of hypothermia increase perioperative risk. The article describes in detail the mechanisms of human thermoregulation and their disruption.

Anaesthesia Hypothermia Springer

Open PDF

Koralewski – Heat Balance and Temperature Regulation

Contribution on energy balance and temperature regulation. The metabolic processes of living organisms follow thermodynamic laws and are always associated with heat generation. The rate of energy turnover and thus metabolic intensity is temperature-dependent. The contribution explains van't Hoff's reaction rate–temperature rule and its significance for the human organism.

Heat balance Metabolism Fundamentals

Open PDF

Specht – The Human Body as a Thermal System

Work from Otto von Guericke University Magdeburg. The human body is described from a technical perspective as a biological reactor with an operating temperature of 37 °C. Since ambient temperature is lower, the body continuously releases heat. The contribution covers measurement and control mechanisms of operating temperature, heat dissipation, energy balance, weight change and thermal comfort.

Thermal engineering 37 °C Control

Open PDF

Brandes, Lang & Schmidt – Physiology of Humans (32nd Edition, Springer)

Standard textbook of human physiology with pathophysiology (32nd edition). The chapter on thermoregulation describes the central and peripheral mechanisms of temperature control, the role of the hypothalamus as thermostat, fever, shivering, sweating and adaptation to extreme ambient temperatures.

Textbook Physiology Hypothalamus

Open PDF

Brooks et al. (2023) – Diurnal Rhythms of Wrist Temperature Are Associated with Future Disease Risk

Study using the UK Biobank (Nature Communications). Many chronic diseases are associated with desynchronised sleep–wake cycles, indicating disrupted biorhythms. The researchers investigated the association of wrist temperature rhythms with future disease risk. The results show that disrupted wrist temperature rhythms can be an early warning sign for various conditions.

UK Biobank Biorhythms Disease risk

Open PDF

Fietze – Thermoregulation (Encyclopaedia of Sleep Medicine)

Review article from the Springer Encyclopaedia of Sleep Medicine. Thermoregulation is determined by the set-point of central core body temperature. Regulation is achieved via various feedback mechanisms controlling heat production and heat dissipation. During sleep these processes are fundamentally regulated differently from wakefulness.

Sleep medicine Encyclopaedia Feedback

Open PDF